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Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma

Although GBP1 (guanylate binding protein 1) was among the first interferon-inducible proteins identified, its function is still largely unknown. Epidermal growth factor receptor (EGFR) activation by amplification or mutation is one of the most frequent genetic lesions in a variety of human tumors. T...

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Bibliografiske detaljer
Main Authors: Li, Ming, Mukasa, Akitake, del-Mar Inda, Maria, Zhang, Jianhua, Chin, Lynda, Cavenee, Webster, Furnari, Frank
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244036/
https://ncbi.nlm.nih.gov/pubmed/22162832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111102
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