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Targeting EGFR for Treatment of Glioblastoma: Molecular Basis to Overcome Resistance

Glioblastoma (glioblastoma multiforme; GBM; WHO Grade IV) accounts for the majority of primary malignant brain tumors in adults. Amplification and mutation of the epidermal growth factor receptor (EGFR) gene represent signature genetic abnormalities encountered in GBM. A range of potential therapies...

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Bibliografske podrobnosti
Main Authors: Taylor, Tiffany E., Furnari, Frank B., Cavenee, Webster K.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464093/
https://ncbi.nlm.nih.gov/pubmed/22268382
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