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TAK1 in brain endothelial cells mediates fever and lethargy

Systemic inflammation affects the brain, resulting in fever, anorexia, lethargy, and activation of the hypothalamus–pituitary–adrenal axis. How peripheral inflammatory signals reach the brain is still a matter of debate. One possibility is that, in response to inflammatory stimuli, brain endothelial...

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Bibliografiske detaljer
Main Authors: Ridder, Dirk A., Lang, Ming-Fei, Salinin, Sergei, Röderer, Jan-Peter, Struss, Marcel, Maser-Gluth, Christiane, Schwaninger, Markus
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244031/
https://ncbi.nlm.nih.gov/pubmed/22143887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110398
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