Brain endothelial TAK1 and NEMO safeguard the neurovascular unit

Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB signaling, cause the genetic disease incontinentia pigmenti (IP). This leads to severe neurological symptoms, but the mechanisms underlying brain involvement were unclear. Here, we show that selectively deleting...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Ridder, Dirk A., Wenzel, Jan, Müller, Kristin, Töllner, Kathrin, Tong, Xin-Kang, Assmann, Julian C., Stroobants, Stijn, Weber, Tobias, Niturad, Cristina, Fischer, Lisanne, Lembrich, Beate, Wolburg, Hartwig, Grand’Maison, Marilyn, Papadopoulos, Panayiota, Korpos, Eva, Truchetet, Francois, Rades, Dirk, Sorokin, Lydia M., Schmidt-Supprian, Marc, Bedell, Barry J., Pasparakis, Manolis, Balschun, Detlef, D’Hooge, Rudi, Löscher, Wolfgang, Hamel, Edith, Schwaninger, Markus
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577837/
https://ncbi.nlm.nih.gov/pubmed/26347470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150165
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker