Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

BACKGROUND: Advanced glycations end products increase oxidant stress, inflammation, and neurotoxicity. Serum levels are increased in diabetes and aging. We examined the relationship between serum methylglyoxal derivatives (sMG), and cognitive decline, in 267 non-demented elderly. METHODS: Tobit mixe...

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Detaylı Bibliyografya
Asıl Yazarlar: Beeri, Michal Schnaider, Moshier, Erin, Schmeidler, James, Godbold, James, Uribarri, Jaime, Reddy, Sarah, Sano, Mary, Grossman, Hillel T, Cai, Weijing, Vlassara, Helen, Silverman, Jeremy M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243767/
https://ncbi.nlm.nih.gov/pubmed/22079406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.10.007
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