Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

BACKGROUND: Advanced glycations end products increase oxidant stress, inflammation, and neurotoxicity. Serum levels are increased in diabetes and aging. We examined the relationship between serum methylglyoxal derivatives (sMG), and cognitive decline, in 267 non-demented elderly. METHODS: Tobit mixe...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Beeri, Michal Schnaider, Moshier, Erin, Schmeidler, James, Godbold, James, Uribarri, Jaime, Reddy, Sarah, Sano, Mary, Grossman, Hillel T, Cai, Weijing, Vlassara, Helen, Silverman, Jeremy M
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243767/
https://ncbi.nlm.nih.gov/pubmed/22079406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.10.007
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