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Early Cholinergic Neuronal and Axonal Pathology in Aging and Alzheimer’s Disease

A large body of evidence had indicated that the basal forebrain cholinergic neurons (BFCN) are selectively vulnerable to early degeneration in Alzheimer’s disease (AD). However, recent studies have demonstrated reductions in cortical activity of the cholinergic enzyme choline acetyltransferase (ChAT...

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Detalhes bibliográficos
Main Authors: Geula, Changiz, Nagykery, Nicholas, Nicholas, Alexander, Wu, Chuang-Kuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243760/
https://ncbi.nlm.nih.gov/pubmed/18379437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31816a1df3
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