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Early Cholinergic Neuronal and Axonal Pathology in Aging and Alzheimer’s Disease

A large body of evidence had indicated that the basal forebrain cholinergic neurons (BFCN) are selectively vulnerable to early degeneration in Alzheimer’s disease (AD). However, recent studies have demonstrated reductions in cortical activity of the cholinergic enzyme choline acetyltransferase (ChAT...

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Autors principals: Geula, Changiz, Nagykery, Nicholas, Nicholas, Alexander, Wu, Chuang-Kuo
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243760/
https://ncbi.nlm.nih.gov/pubmed/18379437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31816a1df3
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