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Early Cholinergic Neuronal and Axonal Pathology in Aging and Alzheimer’s Disease

A large body of evidence had indicated that the basal forebrain cholinergic neurons (BFCN) are selectively vulnerable to early degeneration in Alzheimer’s disease (AD). However, recent studies have demonstrated reductions in cortical activity of the cholinergic enzyme choline acetyltransferase (ChAT...

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Autori principali: Geula, Changiz, Nagykery, Nicholas, Nicholas, Alexander, Wu, Chuang-Kuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243760/
https://ncbi.nlm.nih.gov/pubmed/18379437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31816a1df3
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