Loss of Calbindin-D(28K) is Associated with the Full Range of Tangle Pathology within Basal Forebrain Cholinergic Neurons in Alzheimer's Disease

Basal forebrain cholinergic neurons (BFCN) are selectively vulnerable in Alzheimer's disease (AD). We have shown that the majority of BFCN in the human brain contain the calcium binding protein calbindin-D(28K) (CB), a large proportion lose their CB in the course of normal aging, and the BFCN w...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Ahmadian, Saman S., Rezvanian, Aras, Peterson, Melanie, Weintraub, Sandra, Bigio, Eileen H., Mesulam, M.-Marsel, Geula, Changiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641850/
https://ncbi.nlm.nih.gov/pubmed/26417681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.001
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