Loss of Calbindin-D(28K) is Associated with the Full Range of Tangle Pathology within Basal Forebrain Cholinergic Neurons in Alzheimer's Disease

Basal forebrain cholinergic neurons (BFCN) are selectively vulnerable in Alzheimer's disease (AD). We have shown that the majority of BFCN in the human brain contain the calcium binding protein calbindin-D(28K) (CB), a large proportion lose their CB in the course of normal aging, and the BFCN w...

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Publicado en:Neurobiol Aging
Autores principales: Ahmadian, Saman S., Rezvanian, Aras, Peterson, Melanie, Weintraub, Sandra, Bigio, Eileen H., Mesulam, M.-Marsel, Geula, Changiz
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641850/
https://ncbi.nlm.nih.gov/pubmed/26417681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.001
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