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Structural basis of initial RNA polymerase II transcription

During transcription initiation by RNA polymerase (Pol) II, a transient open promoter complex (OC) is converted to an initially transcribing complex (ITC) containing short RNAs, and to a stable elongation complex (EC). We report structures of a Pol II–DNA complex mimicking part of the OC, and of com...

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Bibliografiske detaljer
Main Authors: Cheung, Alan C M, Sainsbury, Sarah, Cramer, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243610/
https://ncbi.nlm.nih.gov/pubmed/22056778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.396
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