Mutant p53 Disrupts Role of ShcA Protein in Balancing Smad Protein-dependent and -independent Signaling Activity of Transforming Growth Factor-β (TGF-β)

Biomarkers are lacking for identifying the switch of transforming growth factor-β (TGF-β) from tumor-suppressing to tumor-promoting. Mutated p53 (mp53) has been suggested to switch TGF-β to a tumor promoter. However, we found that mp53 does not always promote the oncogenic role of TGF-β. Here, we sh...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lin, Shu, Yu, Lan, Yang, Junhua, Liu, Zhao, Karia, Bijal, Bishop, Alexander J. R., Jackson, James, Lozano, Guillermina, Copland, John A., Mu, Xiaoxin, Sun, Beicheng, Sun, Lu-Zhe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243540/
https://ncbi.nlm.nih.gov/pubmed/22039050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265397
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker