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Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress

AIMS: We investigate the role of mitochondrial oxidative stress in mitochondrial proteome remodelling using mouse models of heart failure induced by pressure overload. METHODS AND RESULTS: We demonstrate that mice overexpressing catalase targeted to mitochondria (mCAT) attenuate pressure overload-in...

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Autori principali: Dai, Dao-Fu, Hsieh, Edward J., Liu, Yonggang, Chen, Tony, Beyer, Richard P., Chin, Michael T., MacCoss, Michael J., Rabinovitch, Peter S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243039/
https://ncbi.nlm.nih.gov/pubmed/22012956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr274
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