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The nuclear receptor constitutive active/androstane receptor (CAR) arrests DNA-damaged human hepatocellular carcinoma Huh7 cells at the G2/M phase
Here we have demonstrated that xenobiotic activation of the nuclear receptor CAR (NR1I3) can result in arresting DNA-damaged human hepatocellular carcinoma Huh7 cells at the G2/M phase. Huh7 cells over-expressing CAR were either treated with DMSO, the CAR activator TCPOBOP, or repressor androstenol;...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242902/ https://ncbi.nlm.nih.gov/pubmed/21557330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20783 |
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