Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm

Eitemau Tebyg

• Dietary flavonoids activate the constitutive androstane receptor CAR
  gan: Yao, Ruiquing, et al.
  Cyhoeddwyd: (2010)
• Extracellular Signal-Regulated Kinase Is an Endogenous Signal Retaining the Nuclear Constitutive Active/Androstane Receptor (CAR) in the Cytoplasm of Mouse Primary Hepatocytes
  gan: Koike, Chika, et al.
  Cyhoeddwyd: (2007)
• Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3)
  gan: Mutoh, Shingo, et al.
  Cyhoeddwyd: (2009)
• Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation
  gan: Shizu, Ryota, et al.
  Cyhoeddwyd: (2017)
• Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling
  gan: Mutoh, Shingo, et al.
  Cyhoeddwyd: (2013)