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The impact of glycosylation on monoclonal antibody conformation and stability
Antibody glycosylation is a common post-translational modification and has a critical role in antibody effector function. The use of glycoengineering to produce antibodies with specific glycoforms may be required to achieve the desired therapeutic efficacy. However, the modified molecule could have...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242843/ https://ncbi.nlm.nih.gov/pubmed/22123061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.6.17922 |
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