Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) promise specific correction of disease-causing gene expression. Therapeutic implementation, however, has been forestalled by poor delivery to the appropriate tissue, cell type, and subcellular compartment. Topical administration is...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Moschos, Sterghios A, Frick, Manfred, Taylor, Bruce, Turnpenny, Paul, Graves, Helen, Spink, Karen G, Brady, Kevin, Lamb, David, Collins, David, Rockel, Thomas D, Weber, Markus, Lazari, Ovadia, Perez-Tosar, Luis, Fancy, Sally A, Lapthorn, Chris, Green, Martin X, Evans, Steve, Selby, Matthew, Jones, Gareth, Jones, Lyn, Kearney, Sarah, Mechiche, Houria, Gikunju, Diana, Subramanian, Romesh, Uhlmann, Eugen, Jurk, Marion, Vollmer, Jörg, Ciaramella, Giuseppe, Yeadon, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242665/
https://ncbi.nlm.nih.gov/pubmed/21971426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.206
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