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Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) promise specific correction of disease-causing gene expression. Therapeutic implementation, however, has been forestalled by poor delivery to the appropriate tissue, cell type, and subcellular compartment. Topical administration is...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Moschos, Sterghios A, Frick, Manfred, Taylor, Bruce, Turnpenny, Paul, Graves, Helen, Spink, Karen G, Brady, Kevin, Lamb, David, Collins, David, Rockel, Thomas D, Weber, Markus, Lazari, Ovadia, Perez-Tosar, Luis, Fancy, Sally A, Lapthorn, Chris, Green, Martin X, Evans, Steve, Selby, Matthew, Jones, Gareth, Jones, Lyn, Kearney, Sarah, Mechiche, Houria, Gikunju, Diana, Subramanian, Romesh, Uhlmann, Eugen, Jurk, Marion, Vollmer, Jörg, Ciaramella, Giuseppe, Yeadon, Michael
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: Nature Publishing Group 2011
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242665/
https://ncbi.nlm.nih.gov/pubmed/21971426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.206
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