A Field Trial to Assess a Blood-Stage Malaria Vaccine

BACKGROUND: Blood-stage malaria vaccines are intended to prevent clinical disease. The malaria vaccine FMP2.1/AS02(A), a recombinant protein based on apical membrane antigen 1 (AMA1) from the 3D7 strain of Plasmodium falciparum, has previously been shown to have immunogenicity and acceptable safety...

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Main Authors: Thera, Mahamadou A., Doumbo, Ogobara K., Coulibaly, Drissa, Laurens, Matthew B., Ouattara, Amed, Kone, Abdoulaye K., Guindo, Ando B., Traore, Karim, Traore, Idrissa, Kouriba, Bourema, Diallo, Dapa A., Diarra, Issa, Daou, Modibo, Dolo, Amagana, Tolo, Youssouf, Sissoko, Mahamadou S., Niangaly, Amadou, Sissoko, Mady, Takala-Harrison, Shannon, Lyke, Kirsten E., Wu, Yukun, Blackwelder, William C., Godeaux, Olivier, Vekemans, Johan, Dubois, Marie-Claude, Ballou, W. Ripley, Cohen, Joe, Thompson, Darby, Dube, Tina, Soisson, Lorraine, Diggs, Carter L., House, Brent, Lanar, David E., Dutta, Sheetij, Heppner, D. Gray, Plowe, Christopher V.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242358/
https://ncbi.nlm.nih.gov/pubmed/21916638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1008115
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