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The opposing transcriptional functions of Sin3A and c-Myc are required to maintain tissue homeostasis
How the proto-oncogene c-Myc balances the processes of stem cell self-renewal, proliferation and differentiation in adult tissues is largely unknown. We explored c-Myc’s transcriptional roles at the Epidermal Differentiation Complex (EDC) a locus essential for skin maturation. Binding of c-Myc can s...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242072/ https://ncbi.nlm.nih.gov/pubmed/22101514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2385 |
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