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The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is required to balance stem cell self-renewal and di...

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Detalhes bibliográficos
Main Authors: Blanco, Sandra, Kurowski, Agata, Nichols, Jennifer, Watt, Fiona M., Benitah, Salvador Aznar, Frye, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228827/
https://ncbi.nlm.nih.gov/pubmed/22144916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002403
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