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Tight Regulation of Memory CD8 T Cells Limits Their Effectiveness during Sustained High Viral Load
To design successful vaccines for chronic diseases, an understanding of memory CD8(+) T cell responses to persistent antigen re-stimulation is critical. However, most studies comparing memory and naïve cell responses have only been performed in rapidly cleared acute infections. Herein, by comparing...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241982/ https://ncbi.nlm.nih.gov/pubmed/21856186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.017 |
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