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Aberrant Regulation of the MRP3 Gene in Non-Small Cell Lung Carcinoma

INTRODUCTION: Multidrug-resistance Protein-3 (MRP3), a membrane bound transporter, facilitates efflux of toxic compounds, including certain chemotherapies, out of cells. Aberrant MRP3 expression has been linked to drug resistance in NSCLC. We sought to determine if tumor MRP3 expression patterns cor...

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Detalhes bibliográficos
Main Authors: Mahaffey, Christopher M., Mahaffey, Nichole C., Holland, William, Zhang, Hongqiao, Gandara, David R., Mack, Philip C., Forman, Henry Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241903/
https://ncbi.nlm.nih.gov/pubmed/22089114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318233d753
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