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Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins
Numerous membrane importers rely on accessory water-soluble proteins to capture their substrates. These substrate-binding proteins (SBP) have a strong affinity for their ligands; yet, substrate release onto the low-affinity membrane transporter must occur for uptake to proceed. It is generally accep...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241785/ https://ncbi.nlm.nih.gov/pubmed/22084072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112534108 |
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