PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling

BACKGROUND: Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) regulation of the Rho-like GTPase Cdc42 has a central role in epithelial polarised growth, but effects of this molecular network on apoptosis remain unclear. METHODS: To investigate the role of Cdc42 in PTEN-dependent cell...

Full description

Saved in:
Bibliographic Details
Main Authors: Deevi, R, Fatehullah, A, Jagan, I, Nagaraju, M, Bingham, V, Campbell, F C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241554/
https://ncbi.nlm.nih.gov/pubmed/21952626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.384
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items