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Regulation of ribonucleotide reductase in response to iron deficiency

Ribonucleotide reductase (RNR) is an essential enzyme required for DNA synthesis and repair. Although iron is necessary for class Ia RNR activity, little is known about the mechanisms that control RNR in response to iron deficiency. In this work, we demonstrate that yeast cells control RNR function...

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Autori principali: Sanvisens, Nerea, Bañó, M. Carmen, Huang, Mingxia, Puig, Sergi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240860/
https://ncbi.nlm.nih.gov/pubmed/22152479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.021
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