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Regulation of ribonucleotide reductase in response to iron deficiency

Ribonucleotide reductase (RNR) is an essential enzyme required for DNA synthesis and repair. Although iron is necessary for class Ia RNR activity, little is known about the mechanisms that control RNR in response to iron deficiency. In this work, we demonstrate that yeast cells control RNR function...

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Detalhes bibliográficos
Main Authors: Sanvisens, Nerea, Bañó, M. Carmen, Huang, Mingxia, Puig, Sergi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240860/
https://ncbi.nlm.nih.gov/pubmed/22152479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.021
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