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Ribonucleotide reductase metallocofactor: assembly, maintenance and inhibition
Ribonucleotide reductase (RNR) supplies cellular deoxyribonucleotide triphosphates (dNTP) pools by converting ribonucleotides to the corresponding deoxy forms using radical-based chemistry. Eukaryotic RNR comprises α and β subunits: α contains the catalytic and allosteric sites; β houses a diferric-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041730/ https://ncbi.nlm.nih.gov/pubmed/24899886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-014-1302-6 |
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