Retooling Manganese(III) Porphyrin-Based Peroxynitrite Decomposition Catalysts for Selectivity and Oral Activity: A Potential New Strategy for Treating Chronic Pain

Redox-active metalloporphyrins represent the most well characterized class of catalysts capable of attenuating oxidative stress in vivo through the direct interception and decomposition of superoxide and peroxynitrite. While many interesting pharmacological probes have emerged from these studies, fe...

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Bibliografiske detaljer
Main Authors: Rausaria, Smita, Ghaffari, Mahsa M.E., Kamadulski, Andrew, Rodgers, Kenny, Bryant, Leesa, Chen, Zhoumou, Doyle, Tim, Shaw, Michael J., Salvemini, Daniela, Neumann, William L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240686/
https://ncbi.nlm.nih.gov/pubmed/22082008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201233r
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