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Manganese(III) Complexes of Bis-Hydroxyphenyldipyrromethenes are Potent Orally Active Peroxynitrite Scavengers

We report a new series of bis-cyclohexano-fused Mn(III) complexes of bis-hydroxyphenyl-dipyrromethenes (DIPYs) 4a–c as potent and orally active peroxynitrite scavengers. Complexes 4a–c have been shown to reduce peroxynitrite through a 2-electron mechanism thereby forming the corresponding Mn(V)O spe...

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Detalhes bibliográficos
Main Authors: Rausaria, Smita, Kamadulski, Andrew, Rath, Nigam P., Bryant, Leesa, Chen, Zhoumou, Salvemini, Daniela, Neumann, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075724/
https://ncbi.nlm.nih.gov/pubmed/21370860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110427e
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