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Role for Peroxynitrite in Sphingosine-1-Phosphate Induced Hyperalgesia in Rats

Sphingosine-1-phosphate (S1P) is an important mediator of inflammation recently shown in in vitro studies to increase the excitability of small diameter sensory neurons at least in part via activation of the S1P(1) receptor subtype. Activation of S1PR(1) has been reported to increase the formation o...

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Autors principals: Doyle, Tim, Finley, Amanda, Chen, Zhoumou, Salvemini, Daniela
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039096/
https://ncbi.nlm.nih.gov/pubmed/21239112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.12.011
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