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The chemical synthesis of oligoribonucleotides VII. A comparison of condensing agents in the coupling of silylated ribonucleosides.

The t-butyldimethylsilyl group is shown to be an ideal protecting group for the 2T-hydroxyl function of ribonucleosides during the synthesis of ribonucleotides using any of nine commonly used condensing agents. The phosphite coupling procedure compares favorably with all of the widely used condensin...

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Publicat a:Nucleic Acids Res
Autors principals: Ogilvie, K K, Pon, R T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1980
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7433136/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.9.2105
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