The chemical synthesis of oligoribonucleotides VII. A comparison of condensing agents in the coupling of silylated ribonucleosides.
The t-butyldimethylsilyl group is shown to be an ideal protecting group for the 2T-hydroxyl function of ribonucleosides during the synthesis of ribonucleotides using any of nine commonly used condensing agents. The phosphite coupling procedure compares favorably with all of the widely used condensin...
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| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1980
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7433136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.9.2105 |
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