Suppression of tumorigenicity with continued expression of the c-Ha-ras oncogene in EJ bladder carcinoma-human fibroblast hybrid cells.

A human tumor cell line (EJ) expressing an activated c-Ha-ras oncogene was fused with a normal human fibroblast cell line. This fusion resulted in hybrids that behaved as transformed cells in culture but failed to form tumors in nude (athymic) mice. After repeated cell passage, two tumorigenic segre...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Geiser, A G, Der, C J, Marshall, C J, Stanbridge, E J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5209
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