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Suppression of tumorigenicity with continued expression of the c-Ha-ras oncogene in EJ bladder carcinoma-human fibroblast hybrid cells.

A human tumor cell line (EJ) expressing an activated c-Ha-ras oncogene was fused with a normal human fibroblast cell line. This fusion resulted in hybrids that behaved as transformed cells in culture but failed to form tumors in nude (athymic) mice. After repeated cell passage, two tumorigenic segre...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Geiser, A G, Der, C J, Marshall, C J, Stanbridge, E J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5209
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