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Suppression of tumorigenicity with continued expression of the c-Ha-ras oncogene in EJ bladder carcinoma-human fibroblast hybrid cells.

A human tumor cell line (EJ) expressing an activated c-Ha-ras oncogene was fused with a normal human fibroblast cell line. This fusion resulted in hybrids that behaved as transformed cells in culture but failed to form tumors in nude (athymic) mice. After repeated cell passage, two tumorigenic segre...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Geiser, A G, Der, C J, Marshall, C J, Stanbridge, E J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5209
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