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Oncogenicity by adenovirus is not determined by the transforming region only.

We have constructed a nondefective recombinant virus between the nononcogenic adenovirus 5 (Ad5) and the highly oncogenic Ad12. The recombinant genome consists essentially of Ad5 sequences, with the exception of the transforming early region 1 (E1) which is derived from Ad12. HeLa cells infected wit...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Bernards, R, de Leeuw, M G, Vaessen, M J, Houweling, A, van der Eb, A J
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 1984
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6328015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.3.847-853.1984
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