Oncogenicity by adenovirus is not determined by the transforming region only.

We have constructed a nondefective recombinant virus between the nononcogenic adenovirus 5 (Ad5) and the highly oncogenic Ad12. The recombinant genome consists essentially of Ad5 sequences, with the exception of the transforming early region 1 (E1) which is derived from Ad12. HeLa cells infected wit...

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Bibliographic Details
Main Authors: Bernards, R, de Leeuw, M G, Vaessen, M J, Houweling, A, van der Eb, A J
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC255745/
https://ncbi.nlm.nih.gov/pubmed/6328015
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