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Mutations of the ras gene product p21 that abolish guanine nucleotide binding.

We have constructed several point mutations affecting the GTP-binding site of p21, the ras-encoded protein. Both lysine (116K) and tyrosine (116Y) mutations of asparagine-116, which, by analogy with the crystal structure of elongation factor Tu (EF-Tu), has critical interactions with the guanine bas...

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Bibliografiske detaljer
Main Authors: Clanton, D J, Hattori, S, Shih, T Y
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323893/
https://ncbi.nlm.nih.gov/pubmed/3014531
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