Mutations of the ras gene product p21 that abolish guanine nucleotide binding.
We have constructed several point mutations affecting the GTP-binding site of p21, the ras-encoded protein. Both lysine (116K) and tyrosine (116Y) mutations of asparagine-116, which, by analogy with the crystal structure of elongation factor Tu (EF-Tu), has critical interactions with the guanine bas...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1986
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5076 |
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