Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.

H2O2, in concentrations achieved in the proximity of stimulated leukocytes, induces injury and lysis of target cells. This may be an important aspect of inflammatory injury of tissues. Cell lysis in two target cells, the murine macrophage-like tumor cell line P388D1 and human peripheral lymphocytes,...

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Hlavní autoři: Schraufstatter, I U, Hyslop, P A, Hinshaw, D B, Spragg, R G, Sklar, L A, Cochrane, C G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC323853/
https://ncbi.nlm.nih.gov/pubmed/2941760
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