Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.

H2O2, in concentrations achieved in the proximity of stimulated leukocytes, induces injury and lysis of target cells. This may be an important aspect of inflammatory injury of tissues. Cell lysis in two target cells, the murine macrophage-like tumor cell line P388D1 and human peripheral lymphocytes,...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Schraufstatter, I U, Hyslop, P A, Hinshaw, D B, Spragg, R G, Sklar, L A, Cochrane, C G
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2941760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4908
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