Polyadenosine diphosphate-ribose polymerase inhibitors: advances, implications, and challenges in tumor radiotherapy sensitization

Polyadenosine diphosphate-ribose polymerase (PARP) is a key modifying enzyme in cells, which participates in single-strand break repair and indirectly affects double-strand break repair. PARP inhibitors have shown great potential in oncotherapy by exploiting DNA damage repair pathways, and several s...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yi Zhang, Lijie Liang, Zheng Li, Ying Huang, Ming Jiang, Bingwen Zou, Yong Xu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2023-12-01
Sarja:	Frontiers in Oncology
Aiheet:	Polyadenosine diphosphate-ribose polymerase (PARP) cancer radiation therapy radiotherapy sensitization PARP
Linkit:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1295579/full
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!