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A46, a Benzothiophene Derived Compound, Suppresses Jak2-Mediated Pathologic Cell Growth

Hyperkinetic Jak2 tyrosine kinase signaling has been implicated in several hematological disorders including the myeloproliferative neoplasms (MPNs). Effective Jak2 inhibitors can thus have significant therapeutic potential. Here, using structure based virtual screening, we identified a benzothiophe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Majumder, Anurima, Magis, Andrew T., Park, Sung O., Figueroa, Nicholas C., Baskin, Rebekah, Kirabo, Annet, Allan, Robert W., Zhao, Zhizhuang Joe, Bisht, Kirpal S., Keserű, György M., Sayeski, Peter P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237899/
https://ncbi.nlm.nih.gov/pubmed/22019628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.10.003
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