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Post-treatment with the Combination of AICAR and Carnitine Improves Renal Function after Ischemia/Reperfusion Injury

Renal ischemia/reperfusion (I/R) injury is a major clinical problem where main metabolic pathways are compromised and cellular homeostasis crashes after ATP depletion. Fatty acids are major energy source in the kidneys. Carnitine palmitoyltransferase I (CPT1), a mitochondrial membrane enzyme, utiliz...

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Bibliographische Detailangaben
Hauptverfasser: Idrovo, Juan-Pablo, Yang, Weng-Lang, Matsuda, Akihisa, Nicastro, Jeffrey, Coppa, Gene F., Wang, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237783/
https://ncbi.nlm.nih.gov/pubmed/21841537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31823185d7
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