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Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective

Klotho is an antiaging substance with pleiotropic actions including regulation of mineral metabolism. It is highly expressed in the kidney and is present in the circulation and urine but its role in acute kidney injury (AKI) is unknown. We found that ischemia–reperfusion injury (IRI) in rodents redu...

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Hlavní autoři: Hu, Ming-Chang, Shi, Mingjun, Zhang, Jianning, Quiñones, Henry, Kuro-o, Makoto, Moe, Orson W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237296/
https://ncbi.nlm.nih.gov/pubmed/20861825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.328
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