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Probabilistic reconstruction of the tumor progression process in gene regulatory networks in the presence of uncertainty

BACKGROUND: Accumulation of gene mutations in cells is known to be responsible for tumor progression, driving it from benign states to malignant states. However, previous studies have shown that the detailed sequence of gene mutations, or the steps in tumor progression, may vary from tumor to tumor,...

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Hlavní autoři: Esfahani, Mohammad Shahrokh, Yoon, Byung-Jun, Dougherty, Edward R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236852/
https://ncbi.nlm.nih.gov/pubmed/22166046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S10-S9
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