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An experimental design framework for Markovian gene regulatory networks under stationary control policy
BACKGROUND: A fundamental problem for translational genomics is to find optimal therapies based on gene regulatory intervention. Dynamic intervention involves a control policy that optimally reduces a cost function based on phenotype by externally altering the state of the network over time. When a...
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| Publicado no: | BMC Syst Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6302376/ https://ncbi.nlm.nih.gov/pubmed/30577732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0649-8 |
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