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Probabilistic reconstruction of the tumor progression process in gene regulatory networks in the presence of uncertainty
BACKGROUND: Accumulation of gene mutations in cells is known to be responsible for tumor progression, driving it from benign states to malignant states. However, previous studies have shown that the detailed sequence of gene mutations, or the steps in tumor progression, may vary from tumor to tumor,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236852/ https://ncbi.nlm.nih.gov/pubmed/22166046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S10-S9 |
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