Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1

Gemcitabine is a deoxycytidine analog used in the treatment of various solid tumors. However, tumors often develop resistances over time, which becomes a major issue for most gemcitabine-related chemotherapies. In the present study, a previously reported stearoyl gemcitabine nanoparticle formulation...

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Hlavní autoři: Chung, Woon-Gye, Sandoval, Michael A., Sloat, Brian R., Lansakara-P., Dharmika S. P., Cui, Zhengrong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236813/
https://ncbi.nlm.nih.gov/pubmed/21851843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.08.004
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